📌 Keep customer conversations, notes, and next steps together with HubSpot Smart CRM:
Try HubSpot - https://clickhubspot.com/9b86a2
Greg Brockman co-founded OpenAI and previously served as CTO of Stripe. He says AI could bring a “massive renaissance of entrepreneurship” over the next year or two. But what should you actually ask AI to do—and what’s worth building when the models keep getting better?
In this episode, I show Greg the AI app I built to prepare for our interview and ask how to make it more ambitious. We talk about why he no longer writes software himself, what AI could do for a small watch store, why knowing your customers still matters, and how his own AI agent helps him work. Greg also shares where to start if you have just one hour.
*Timestamps:*
00:00 — Why aren’t we using more of what AI can do?
00:59 — What a proactive AI assistant could do for you
02:16 — Why Greg no longer writes software himself
04:15 — I show Greg the AI app I built for this interview
07:10 — What small-business owners should focus on
08:39 — The watch store and the world’s best programmer
09:18 — Raising the ceiling of ambition
10:01 — What makes an AI app worth paying for?
11:16 — The coming renaissance of entrepreneurship
12:56 — HubSpot Smart CRM
13:50 — How to build something better models won’t make obsolete
15:48 — Why domain expertise is an AI advantage
17:38 — Greg’s AI briefing agent
19:48 — How OpenAI measures AI’s effect on productivity
20:59 — Greg’s AI chief of staff
21:54 — When is more AI compute worth it?
23:51 — Where to start with agents—and when to automate
25:29 — What should stay under human control?
26:18 — What to try with AI if you have one hour
27:48 — What work with AI could look like in five years
*Links:*
📩 Follow my Newsletter (Future Proof): https://siliconvalleygirl.beehiiv.com/?utm_source=youtube&utm_medium=video&utm_campaign=futureproof-sub&utm_content=Greg-Brockman
🔗 Instagram: https://www.instagram.com/siliconvalleygirl/
𝕏 : https://x.com/siliconvalleymm
📌 My Companies & Products: https://Marinamogilko.co
30:15
📌 Keep customer conversations, notes, and next steps together with HubSpot Smart CRM:
Try HubSpot - https://clickhubspot.com/9b86a2
Greg Brockman co-founded OpenAI and previously served as CTO of Stripe. He says AI could bring a “massive renaissance of entrepreneurship” over the next year or two. But what should you actually ask AI to do—and what’s worth building when the models keep getting better?
In this episode, I show Greg the AI app I built to prepare for our interview and ask how to make it more ambitious. We talk about why he no longer writes software himself, what AI could do for a small watch store, why knowing your customers still matters, and how his own AI agent helps him work. Greg also shares where to start if you have just one hour.
*Timestamps:*
00:00 — Why aren’t we using more of what AI can do?
00:59 — What a proactive AI assistant could do for you
02:16 — Why Greg no longer writes software himself
04:15 — I show Greg the AI app I built for this interview
07:10 — What small-business owners should focus on
08:39 — The watch store and the world’s best programmer
09:18 — Raising the ceiling of ambition
10:01 — What makes an AI app worth paying for?
11:16 — The coming renaissance of entrepreneurship
12:56 — HubSpot Smart CRM
13:50 — How to build something better models won’t make obsolete
15:48 — Why domain expertise is an AI advantage
17:38 — Greg’s AI briefing agent
19:48 — How OpenAI measures AI’s effect on productivity
20:59 — Greg’s AI chief of staff
21:54 — When is more AI compute worth it?
23:51 — Where to start with agents—and when to automate
25:29 — What should stay under human control?
26:18 — What to try with AI if you have one hour
27:48 — What work with AI could look like in five years
*Links:*
📩 Follow my Newsletter (Future Proof): https://siliconvalleygirl.beehiiv.com/?utm_source=youtube&utm_medium=video&utm_campaign=futureproof-sub&utm_content=Greg-Brockman
🔗 Instagram: https://www.instagram.com/siliconvalleygirl/
𝕏 : https://x.com/siliconvalleymm
📌 My Companies & Products: https://Marinamogilko.co
Dr. Jonathan Chen is a Stanford physician and computer scientist who teaches doctors how to use AI. His team found that GPT-4 alone outperformed doctors using it on diagnostic reasoning tasks. But being smarter doesn’t automatically make AI trustworthy. In this episode, we break down how to ask AI about your health, use your medical records to prepare for appointments, and avoid steering a chatbot toward the answer you want to hear. Jonathan also explains why AI can leave out critical information, why more health screening isn’t always better, and what doctors still need to do when a computer knows more than they do.
📩 Follow my Newsletter: https://siliconvalleygirl.beehiiv.com/?utm_source=youtube&utm_medium=video&utm_campaign=futureproof-sub&utm_content=JonathanChen
📌 Bring your team’s research, context, and AI workflow together on one canvas:
Try Miro – https://miro.pxf.io/2RLQv0
*Timestamps:*
00:00 — Is AI smarter than your doctor?
01:38 — How AI outperformed doctors using AI
03:33 — How your questions can steer AI toward the wrong answer
05:12 — Using your medical records to prepare for appointments
08:27 — What AI can help with and when to double-check
11:28 — How to ask about symptoms without leading the AI
12:57 — Which AI should you use for health questions?
15:45 — Does telling AI “I’m a doctor” help?
20:48 — Can you give AI too much medical history?
24:05 — Are full-body scans and extra tests worth it?
28:21 — When genetic testing can make a difference
29:28 — Can AI help detect cancer earlier?
33:31 — What to ask AI when doctors can’t find an answer
35:15 — Can relying on AI make you lose your skills?
36:51 — What makes a good doctor when AI knows more?
39:39 — AI doctors and automated prescriptions
41:39 — Will AI cure all diseases in 10 years?
42:24 — What better access to care could change
44:52 — Who should make the final decision?
47:10 — Always use multiple AI models for a second opinion
*Links:*
🔗 My Instagram: https://www.instagram.com/siliconvalleygirl/
📌 My Companies & Products: https://partnerships.marinamogilko.co
48:34
Dr. Jonathan Chen is a Stanford physician and computer scientist who teaches doctors how to use AI. His team found that GPT-4 alone outperformed doctors using it on diagnostic reasoning tasks. But being smarter doesn’t automatically make AI trustworthy. In this episode, we break down how to ask AI about your health, use your medical records to prepare for appointments, and avoid steering a chatbot toward the answer you want to hear. Jonathan also explains why AI can leave out critical information, why more health screening isn’t always better, and what doctors still need to do when a computer knows more than they do.
📩 Follow my Newsletter: https://siliconvalleygirl.beehiiv.com/?utm_source=youtube&utm_medium=video&utm_campaign=futureproof-sub&utm_content=JonathanChen
📌 Bring your team’s research, context, and AI workflow together on one canvas:
Try Miro – https://miro.pxf.io/2RLQv0
*Timestamps:*
00:00 — Is AI smarter than your doctor?
01:38 — How AI outperformed doctors using AI
03:33 — How your questions can steer AI toward the wrong answer
05:12 — Using your medical records to prepare for appointments
08:27 — What AI can help with and when to double-check
11:28 — How to ask about symptoms without leading the AI
12:57 — Which AI should you use for health questions?
15:45 — Does telling AI “I’m a doctor” help?
20:48 — Can you give AI too much medical history?
24:05 — Are full-body scans and extra tests worth it?
28:21 — When genetic testing can make a difference
29:28 — Can AI help detect cancer earlier?
33:31 — What to ask AI when doctors can’t find an answer
35:15 — Can relying on AI make you lose your skills?
36:51 — What makes a good doctor when AI knows more?
39:39 — AI doctors and automated prescriptions
41:39 — Will AI cure all diseases in 10 years?
42:24 — What better access to care could change
44:52 — Who should make the final decision?
47:10 — Always use multiple AI models for a second opinion
*Links:*
🔗 My Instagram: https://www.instagram.com/siliconvalleygirl/
📌 My Companies & Products: https://partnerships.marinamogilko.co
