Alex Rives on ESMFold, BioHub's open source system for scientific discovery in protein biology:
1. They folded over 1.1 billion proteins and predicted every single structure.
2. The model learned protein biology so well it hit state of the art on every benchmark they threw at it.
3. They never once trained it on antibodies, but antibody design came out the other side anyway.
Experiments that used to mean screening millions of antibodies in a lab can now just run on a computer.